THE NEUROMUSCULAR COMPLICATIONS OF HIV INFECTIONS Essay

THE neuromuscular COMPLICATIONS OF human immunodeficiency virus INFECTIONS - shew archetypedistal symmetric, a lot dire sensorimotor polyneuropathy and cytomegalovirus contagion ar to a greater extent public in the new-made stages of acquired resistant deficiency syndrome.6. Aintegrated data processing and CIDP whitethorn be the sign materialization of disease, connect to autoimmune dysfunction. CSF bespeaks pleocytosis and increase protein. hardihood conduction studies (NCSs) and biopsy atomic number 18 congenial with demyelination.7. Mononeuropathy multiplex is an inflammatory result in the other(a) stages of disease. new-fashioned MM is typic aloney associated with cytomegalovirus cloudion. may come forth as IDP or PP. electromyogram and NCS show axonal retrogression and irregular closeness. SDF shows pleocytosis and promote protein level.8. advancing polyradiculopathy (PP) is typically associated with cytomegalovirus and herpes virus infections. extr emely mobile antiretroviral therapy (HAART) has trim down the incidence of PP. CSF shows pleocytosis and raise protein level. It typically presents with a cauda equina equal picture, and electromyogram shows denervation of the disappoint extremities. NCSs be gently slow.10. Myopathy shows proximal impuissance and is substantiate with EMG. promote CK may as well as be seen, and heftiness biopsy tail assembly be helpful, demonstrating humiliation and inflammation. human immunodeficiency virus- colligate myopathy moldiness be severalize from toxin (AZT) related myopathies. (1) encircling(prenominal) neuropathy is the commonest neurologic overturn associated with human immunodeficiency virus infection. though symptomatic computer encircling(prenominal) neuropathy is observed in 10% to 15% of HIV infected patients, ghoulish tell of involvement of skirting(prenominal) brass instrument is seen just about all cases of end-stage AIDS patients.Although the pathogenesis of distal sensational polyneuropathy is unclear, the see is associated with stultification of the patients immune system. A chief(a) viral etiology is unlikely, since military personnel Immunodeficiency virus does non infect peripheral core Schwann cells or axons. The similarities in clinical and pathological findings of HIV-associated distal sensory(prenominal) polyneuropathy (DSP) and vitamin B12 deficiency-related